To remove a lesson from your course click on the course in the Custom Courses page. Access this page by clicking the top left hamburger icon and open the Left Bar Side Panel and click on tab "Courses". Then click Course playlist.
After clicking on your custom course your lessons will appear. Simply click the lesson you wish to remove
You will be brought to the lesson video page where you can click "Unsave Lesson" below the video to remove the lesson from your course playlist